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The current research displays the HexaPro stabilized prefusion spike ectodomain is usually a hugely steady conformation. Its generation is suited to quick and price-helpful manufacturing. It is additionally conveniently transported, beating logistical boundaries.
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The subunit spike vaccine prospect HexaPro generated impressive neutralizing responses. This spike protein ectodomain has 4 more proline substitutions to stabilize the prefusion conformation continue to even further. This is often in the S2 domain in the stabilized S-2P spike.
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